Dozmorov Lab

Publications

Google Scholar | PubMed bibliography | ORCID

Lead/senior author publications

  • Wall BPG, Nguyen M, Harrell JC, Dozmorov MG∗. Machine and deep learning methods for predicting 3D genome organization. Methods Mol Biol._ 2025. PMID, DOI , Preprint

  • Dozmorov MG∗, Marshall MA, Rashid NS, Grible JM, Valentine A, Olex AL, Murthy K, Chakraborty A, Reyna J, Figueroa DS, Hinojosa-Gonzalez L, Da-Inn Lee E, Baur BA, Roy S, Ay F, Harrell JC. Rewiring of the 3D genome during acquisition of carboplatin resistance in a triple-negative breast cancer patient-derived xenograft. Sci Rep. 2023 Apr 3, PMID, DOI

  • Dozmorov MG∗, Mu W, Davis ES, Lee S, Triche TJ Jr, Phanstiel DH, Love MI. CTCF: an R/bioconductor data package of human and mouse CTCF binding sites Bioinformatics Advances, PMID, DOI

  • Stilianoudakis SC, Marshall MA, Dozmorov MG∗. preciseTAD: A transfer learning framework for 3D domain boundary prediction at base-pair resolution Bioinformatics (06 November 2021). PMID, DOI

  • Dong X∗, Liu C, Dozmorov M∗. Review of multi-omics data resources and integrative analysis for human brain disorders. Brief Funct Genomics. 2021 May 8, PMID, DOI

  • Dozmorov MG∗, Tyc KM, Sheffield NC, Boyd DC, Olex AL, Reed J, Harrell JC∗. Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines. Gigascience. 2021 Apr 21, PMID, DOI

  • Dozmorov MG∗, Cresswell KG, Bacanu SA, Craver C, Reimers M, Kendler KS. A method for estimating coherence of molecular mechanisms in major human disease and traits. BMC Bioinformatics. 2020 Oct 21. PMID, DOI

  • Cresswell KG, Stansfield JS, Dozmorov MG∗. SpectralTAD: An R Package for Defining a Hierarchy of Topologically Associated Domains Using Spectral Clustering. BMC Bioinformatics 21, no. 1 (December 2020): 319. DOI

  • Cresswell KG, Dozmorov MG∗. TADCompare: An R Package for Differential and Temporal Analysis of Topologically Associated Domains. Front Genet. 2020 Mar 10. PMID, DOI

  • Stansfield JC, Tran D, Nguyen T, Dozmorov MG∗. R Tutorial: Detection of Differentially Interacting Chromatin Regions From Multiple Hi-C Datasets. Curr Protoc Bioinformatics. 2019 May 24. PMID, DOI

  • Stansfield JC, Cresswell KG, Dozmorov MG∗. multiHiCcompare: joint normalization and comparative analysis of complex Hi-C experiments. Bioinformatics. 2019 Jan 22. PMID, DOI

  • Dozmorov MG∗. GitHub Statistics as a Measure of the Impact of Open-Source Bioinformatics Software. Front Bioeng Biotechnol. 2018 Dec 12. PMID, DOI

  • Dozmorov MG∗. Reforming disease classification system-are we there yet? Ann Transl Med. 2018 Nov 6. PMID, DOI

  • Stansfield JC, Cresswell KG, Vladimirov VI, Dozmorov MG∗. HiCcompare: an R-package for joint normalization and comparison of HI-C datasets. BMC Bioinformatics. 2018 Jul 31. PMID, DOI

  • Dozmorov MG∗. Disease classification: from phenotypic similarity to integrative genomics and beyond. Brief Bioinform. 2018 Jun 22. PMID, DOI

  • Dozmorov MG∗. Epigenomic annotation-based interpretation of genomic data: from enrichment analysis to machine learning. Bioinformatics. 2017 Oct 15. PMID, DOI

  • Dozmorov MG, Coit P, Maksimowicz-McKinnon K, Sawalha AH. Age-associated DNA methylation changes in naive CD4+ T cells suggest an evolving autoimmune epigenotype in aging T cells. Epigenomics. 2017. PMID, DOI

  • Glass ER, Dozmorov MG∗. Improving sensitivity of linear regression-based cell type-specific differential expression deconvolution with per-gene vs. global significance threshold. BMC Bioinformatics 2016 Oct 6. PMID, DOI

  • Dozmorov MG∗, Cara LR, Giles CB, Wren JD. GenomeRunner web server: Regulatory similarity and differences define the functional impact of SNP sets. Bioinformatics 2016 Apr 1. PMID, DOI

  • Dozmorov MG∗, Dominguez N, Bean K, Macwana S, Roberts V, Glass E, James JA, Guthridge JM. B cell and monocyte contribution to systemic lupus erythematosus identified by cell-type-specific differential expression analysis in RNA-seq data. Bioinformatics and Biology Insights. 2015 Oct 8. PMID, DOI

  • Dozmorov MG∗, Adrianto I, Giles CB, Glass E, Glenn SB, Montgomery C, Sivils KL, Olson LE, Iwayama T, Freeman WM, Lessard CJ, Wren JD∗. Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data. BMC Bioinformatics. 2015 Sep 25. PMID, DOI

  • Dozmorov MG∗. Polycomb Repressive Complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes. Epigenetics. 2015 Apr 16. PMID, DOI

  • Dozmorov MG, Yang Q, Wu W, Wren J, Suhail MM, Woolley CL, Young DG, Fung KM, Lin HK. Differential effects of selective frankincense (Ru Xiang) essential oil versus non-selective sandalwood (Tan Xiang) essential oil on cultured bladder cancer cells: a microarray and bioinformatics study. Chin Med. 2014 Jul 2. PMID, DOI

  • Dozmorov MG∗, Wren JD, Alarcón-Riquelme ME. Epigenomic elements enriched in the promoters of autoimmunity susceptibility genes. Epigenetics. 2013 Nov 8. PMID, DOI

  • Dozmorov MG∗, Giles CB, Koelsch KA, Wren JD∗. Systematic classification of non-coding RNAs by epigenomic similarity. BMC Bioinformatics. 2013, Oct 9. Best paper of the MCBIOS X conference. PMID, DOI

  • Dozmorov MG∗, Cara LR, Giles CB, Wren JD∗. GenomeRunner: automating genome exploration. Bioinformatics. 2012 Feb 1. PMID, DOI

  • Dozmorov MG, Wren JD. High-throughput processing and normalization of one-color microarrays for transcriptional meta-analyses. BMC Bioinformatics. 2011 Oct 18. PMID, DOI

  • Dozmorov MG, Giles CB, Wren JD. Predicting gene ontology from a global meta-analysis of 1-color microarray experiments. BMC Bioinformatics. 2011 Oct 18. PMID, DOI

  • Dozmorov M, Stone R 2nd, Clifford JL, Sabichi AL, Engles CD, Hauser PJ, Culkin DJ, Hurst RE. System level changes in gene expression in maturing bladder mucosa. J Urol. 2011. PMID, DOI

  • Dozmorov MG, Azzarello JT, Wren JD, Fung KM, Yang Q, Davis JS, Hurst RE, Culkin DJ, Penning TM, Lin HK. Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression. BMC Cancer. 2010 Dec 6. PMID, DOI

  • Dozmorov MG, Guthridge JM, Hurst RE, Dozmorov IM. A comprehensive and universal method for assessing the performance of differential gene expression analyses. PLoS One. 2010 Sep 9. PMID, DOI

  • Dozmorov M, Wu W, Chakrabarty K, Booth JL, Hurst RE, Coggeshall KM, Metcalf JP. Gene expression profiling of human alveolar macrophages infected by B. anthracis spores demonstrates TNF-alpha and NF-kappab are key components of the innate immune response to the pathogen. BMC Infect Dis. 2009 Sep 10. PMID, DOI

  • Dozmorov MG, Hurst RE, Culkin DJ, Kropp BP, Frank MB, Osban J, Penning TM, Lin HK. Unique patterns of molecular profiling between human prostate cancer LNCaP and PC-3 cells. Prostate. 2009 Jul 1. PMID, DOI

  • Dozmorov MG, Kyker KD, Hauser PJ, Saban R, Buethe DD, Dozmorov I, Centola MB, Culkin DJ, Hurst RE. From microarray to biology: an integrated experimental, statistical and in silico analysis of how the extracellular matrix modulates the phenotype of cancer cells. BMC Bioinformatics. 2008 Aug 12. PMID, DOI

  • Dozmorov MG, Yang Q, Matwalli A, Hurst RE, Culkin DJ, Kropp BP, Lin HK. 5alpha-androstane-3alpha,17beta-diol selectively activates the canonical PI3K/AKT pathway: a bioinformatics-based evidence for androgen-activated cytoplasmic signaling. Genomic Med. 2007. PMID, DOI

  • Dozmorov MG, Kyker KD, Saban R, Shankar N, Baghdayan AS, Centola MB, Hurst RE. Systems biology approach for mapping the response of human urothelial cells to infection by Enterococcus faecalis. BMC Bioinformatics. 2007 Nov 1. PMID, DOI

  • Dozmorov MG, Kropp BP, Hurst RE, Cheng EY, Lin HK. Differentially expressed gene networks in cultured smooth muscle cells from normal and neuropathic bladder. J Smooth Muscle Res. 2007 Apr. PMID, DOI

  • Dozmorov MG, Li R, Abbas AK, Hellberg F, Farre C, Huang FS, Jilderos B, Wigström H. Contribution of AMPA and NMDA receptors to early and late phases of LTP in hippocampal slices. Neurosci Res. 2006 Jun. PMID, DOI

  • Dozmorov MG, Kyker KD, Saban R, Knowlton N, Dozmorov I, Centola MB, Hurst RE. Analysis of the interaction of extracellular matrix and phenotype of bladder cancer cells. BMC Cancer. 2006 Jan 13. PMID, DOI

  • Dozmorov M, Li R, Xu HP, Jilderos B, Wigström H. Slowly developing depression of N-methyl-D-aspartate receptor mediated responses in young rat hippocampi. BMC Neurosci. 2004 Aug 3. PMID, DOI

  • Dozmorov M, Niu YP, Xu HP, Xiao MY, Li R, Sandberg M, Wigström H. Active decay of composite excitatory postsynaptic potentials in hippocampal slices from young rats. Brain Res. 2003 May 23. PMID, DOI

∗ indicates corresponding author, unless specified otherwise

Equal contributions

  • Lospinoso K∗, Dozmorov M∗, El Fawal N, Raghu R, Chae WJ, Lee ED. Overexpression of ERAP2N in Human Trophoblast Cells Promotes Cell Death. Int J Mol Sci. 2021 Aug 10, PMID, DOI ∗ - equal contribution

  • Dozmorov MG, Bilbo SD, Kollins SH, Zucker N, Do EK, Schechter JC, Zhang JJ, Murphy SK, Hoyo C, Fuemmeler BF. Associations between maternal cytokine levels during gestation and measures of child cognitive abilities and executive functioning. Brain Behav Immun. 2018 Mar 26. PMID, DOI

  • Coit P, Dozmorov MG∗, Merrill JT, McCune J, Maksimowicz-McKinnon K, Wren JD, Sawalha AH. Epigenetic reprogramming in naïve CD4+ T cells favors T cell activation and non-Th1 effector T cell immune response as an early event in lupus flares. Arthritis & Rheumatology 2016 Apr 25. PMID, DOI ∗ - co-first author

  • Delgado-Vega AM, Dozmorov MG∗, Quirós MB, Wu YY, Martínez-García B, Kozyrev SV,Frostegård J, Truedsson L, de Ramón E, González-Escribano MF, Ortego-Centeno N,Pons-Estel BA, D’Alfonso S, Sebastiani GD, Witte T, Lauwerys BR, Endreffy E,Kovács L, Vasconcelos C, da Silva BM, Wren JD, Martin J, Castillejo-López C, Alarcón-Riquelme ME. Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein. Ann Rheum Dis. 2012 jul 7. PMID, DOI ∗ - co-first author

Collaborative publications

  • Sung EA, Dozmorov MG, Song S, Aung T, Park MH, Sime PJ, Chae WJ. Ablation of LRP6 in alpha-smooth muscle actin-expressing cells abrogates lung inflammation and fibrosis upon bleomycin-induced lung injury. bioRxiv [Preprint]. 2024 Sep 10:2024.09.05.611327. doi: 10.1101/2024.09.05.611327. PMID: 39314349

  • Gnatowski ER, Jurmain JL, Dozmorov MG, Wolstenholme JT, Miles MF. Ninein, a candidate gene for ethanol anxiolysis, shows complex exon-specific expression and alternative splicing differences between C57BL/6J and DBA/2J mice. Front Genet. 2024 Sep 11;15:1455616. doi: 10.3389/fgene.2024.1455616. eCollection 2024. PMID: 39323865

  • Gedik H, Peterson R, Chatzinakos C, Dozmorov MG, Vladimirov V, Riley BP, Bacanu SA. A novel multi-omics mendelian randomization method for gene set enrichment and its application to psychiatric disorders. medRxiv [Preprint]. 2024 Apr 15:2024.04.14.24305811. doi: 10.1101/2024.04.14.24305811. PMID: 38699366

  • Floros KV, Fairchild CK, Li J, Zhang K, Roberts JL, Kurupi R, Hu B, Kraskauskiene V, Hosseini N, Shen S, Inge MM, Smith-Fry K, Li L, Sotiriou A, Dalton KM, Jose A, Abdelfadiel EI, Xing Y, Hill RD, Slaughter JM, Shende M, Lorenz MR, Hinojosa MR, Belvin BR, Lai Z, Boikos SA, Stamatouli AM, Lewis JP, Manjili MH, Valerie K, Li R, Banito A, Poklepovic A, Koblinski JE, Siggers T, Dozmorov MG, Jones KB, Radhakrishnan SK, Faber AC. Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma. bioRxiv [Preprint]. 2024 Apr 27:2024.04.25.591023. doi: 10.1101/2024.04.25.591023. PMID: 38712286

  • Zheng X, Dozmorov MG, Espinoza L, Bowes MM, Bastacky S, Sawalha AH. Inducible deletion of Ezh2 in CD4+ T cells inhibits kidney T cell infiltration and prevents interstitial nephritis in MRL/ lpr lupus-prone mice. bioRxiv [Preprint]. 2024 Mar 7. PMID, DOI

  • Abudahab S, Kronfol MM, Dozmorov MG, Campbell T, Jahr FM, Nguyen J, AlAzzeh O, Al Saeedy DY, Victor A, Lee S, Malay S, Lapato DM, Halquist MS, McRae M, Deshpande LS, Slattum PW, Price ET, McClay JL. Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model. Geroscience. 2024 Apr 1. PMID, DOI

  • Chougoni KK, Park H, Damle PK, Mason T, Cheng B, Dcona MM, Szomju B, Dozmorov MG, Idowu MO, Grossman SR. Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma. Oncogenesis. 2023 Nov 10. PMID, DOI

  • Reghupaty SC, Kanwal S, Mendoza RG, Davis E, Li H, Lai Z, Dozmorov MG, Faison MO, Siddiqui RA, Sarkar D. Dysregulation of Type I Interferon (IFN-I) Signaling: A Potential Contributor to Racial Disparity in Hepatocellular Carcinoma (HCC). Cancers (Basel). 2023 Aug 27. PMID, DOI

  • Reghupaty SC, Kanwal S, Mendoza RG, Davis E, Li H, Lai Z, Dozmorov MG, Faison MO, Siddiqui RA, Sarkar D. Dysregulation of Type I Interferon (IFN-I) Signaling: A Potential Contributor to Racial Disparity in Hepatocellular Carcinoma (HCC). Cancers (Basel). 2023 Aug 27. PMID, DOI

  • Mockenhaupt K, Tyc KM, McQuiston A, Gonsiewski AK, Zarei-Kheirabadi M, Hariprashad A, Biswas DD, Gupta AS, Olex AL, Singh SK, Waters MR, Dupree JL, Dozmorov MG, Kordula T. Yin Yang 1 controls cerebellar astrocyte maturation. Glia. 2023 Jul 7. PMID, DOI

  • Zboril EK, Grible JM, Boyd DC, Hairr NS, Leftwich TJ, Esquivel MF, Duong AK, Turner SA, Ferreira-Gonzalez A, Olex AL, Sartorius CA, Dozmorov MG, Harrell JC. Stratification of Tamoxifen Synergistic Combinations for the Treatment of ER+ Breast Cancer. Cancers (Basel). 2023 Jun 14, PMID, DOI

  • Shang S, Li X, Azzo A, Truong T, Dozmorov M, Lyons C, Manna AK, Williams DC Jr, Ginder GD. MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression. Proc Natl Acad Sci U S A. 2023 Jun 20, PMID, DOI

  • Mu W, Davis ES, Lee S, Dozmorov MG, Phanstiel DH, Love MI. bootRanges: flexible generation of null sets of genomic ranges for hypothesis testing. Bioinformatics. 2023 May 4. PMID, DOI

  • Davis ES, Mu W, Lee S, Dozmorov MG, Love MI, Phanstiel DH. matchRanges: generating null hypothesis genomic ranges via covariate-matched sampling. Bioinformatics. 2023 May 4. PMID, DOI

  • Boyd DC, Zboril EK, Olex AL, Leftwich TJ, Hairr NS, Byers HA, Valentine AD, Altman JE, Alzubi MA, Grible JM, Turner SA, Ferreira-Gonzalez A, Dozmorov MG, Harrell JC. Discovering Synergistic Compounds with BYL-719 in PI3K Overactivated Basal-like PDXs. Cancers (Basel). 2023 Mar 3. PMID, DOI

  • Zheng X, Dozmorov MG, Strohlein CE, Bastacky S, Sawalha AH. Ezh2 knockout in B cells impairs plasmablast differentiation and ameliorates lupus-like disease in MRL/lpr mice. Arthritis Rheumatol. 2023 Mar 10, PMID, DOI

  • Komaniecki G, Camarena MDC, Gelsleichter E, Mendoza R, Subler M, Windle JJ, Dozmorov MG, Lai Z, Sarkar D, Lin H. Astrocyte Elevated Gene-1 Cys75 S-Palmitoylation by ZDHHC6 Regulates Its Biological Activity. Biochemistry. 2022 Dec 22. PMID, DOI

  • Weigel C, Maczis MA, Palladino END, Green CD, Maceyka M, Guo C, Wang XY, Dozmorov MG, Milstien S, Spiegel S. Sphingosine kinase 2 in stromal fibroblasts creates a hospitable tumor microenvironment in breast cancer. Cancer Res. 2022 Dec 21. PMID, DOI

  • Rashid NS, Boyd DC, Olex AL, Grible JM, Duong AK, Alzubi MA, Altman JE, Leftwich TJ, Valentine AD, Hairr NS, Zboril EK, Smith TM Jr, Pfefferle AD, Dozmorov MG, Harrell JC. Transcriptomic changes underlying EGFR inhibitor resistance in human and mouse models of basal-like breast cancer. Sci Rep. 2022 Dec 8. PMID, DOI

  • Shang, Shengzhe, Xia Li, Alexander Azzo, Mikhail Dozmorov, Tin Truong, Asit Manna, David C. Williams, and Gordon Ginder. MBD2a-NuRD Binds to the γ-Globin Gene Promoter and Uniquely Forms a Complex Required for Bcl11a Mediated Silencing of Hb F Expression. Blood, November 15, 2022, DOI

  • Manna D, Reghupaty SC, Camarena MDC, Mendoza RG, Subler MA, Koblinski JE, Martin R, Dozmorov MG, Mukhopadhyay ND, Liu J, Qu X, Das SK, Lai Z, Windle JJ, Fisher PB, Sarkar D. Melanoma differentiation associated gene-9/syndecan binding protein promotes hepatocellular carcinoma. Hepatology. 2022 Sep 19. PMID, DOI News1, News2

  • Sheeba Jacob, Tia H Turner, Jinyang Cai, Konstantinos V Floros, Ann K Yu, Colin M Coon, Rishabh Khatri, Mohammad A Alzubi, Charles T Jakubik, Ynes M Bouck, Madhavi Puchalapalli, Mayuri Shende, Mikhail G Dozmorov, Sosipatros A Boikos, Bin Hu, J Chuck Harrell, Cyril H Benes, Jennifer E Koblinski, Carlotta Costa, Anthony C Faber. Genomic screening reveals UBA1 as a potent and druggable target in c-MYC-high TNBC models. PNAS Nexus. 11 October 2022. DOI News

  • Jaster AM, Younkin J, Cuddy T, de la Fuente Revenga M, Poklis JL, Dozmorov MG, González-Maeso J. Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice. Neurosci Lett. 2022 Aug 10, PMID, DOI

  • Cai J, Jacob S, Kurupi R, Dalton KM, Coon C, Greninger P, Egan RK, Stein GT, Murchie E, McClanaghan J, Adachi Y, Hirade K, Dozmorov MG, Glod J, Boikos SA, Ebi H, Hao H, Caponigro G, Benes CH, Faber AC. High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition. Cell Rep. 2022 Jul 26, PMID, DOI

  • Green CD, Weigel C, Brown RDR, Bedossa P, Dozmorov M, Sanyal AJ, Spiegel S. A new preclinical model of western diet-induced progression of non-alcoholic steatohepatitis to hepatocellular carcinoma. FASEB J. July 2022, PMID, DOI

  • Mirshahi F, Aqbi HF, Isbell M, Manjili SH, Guo C, Saneshaw M, Bandyopadhyay D, Dozmorov M, Khosla A, Wack K, Carrasco-Zevallos OM, Idowu MO, Wang XY, Sanyal AJ, Manjili MH. Distinct hepatic immunological patterns are associated with the progression or inhibition of hepatocellular carcinoma. Cell Rep. 2022 Mar 1, PMID, DOI

  • Green CD, Dozmorov MG, Spiegel S. Analysis of Liver Responses to Non-alcoholic Steatohepatitis by mRNA-Sequencing. Methods Mol Biol. February 25, 2022, PMID, DOI

  • Hampton JD, Peterson EJ, Katner SJ, Turner TH, Alzubi MA, Harrell JC, Dozmorov MG, Turner JBM, Gigliotti PJ, Kraskauskiene V, Shende M, Idowu MO, Puchallapalli M, Hu B, Litovchick L, Katsuta E, Takabe K, Farrell NP, Koblinski JE. Exploitation of sulfated glycosaminoglycan status for precision medicine of Triplatin in triple-negative breast cancer. Mol Cancer Ther. 2021 Nov 23. PMID, DOI

  • Floros KV, Chawla AT, Johnson-Berro MO, Khatri R, Stamatouli AM, Boikos SA, Dozmorov MG, Cowart LA, Faber AC. MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma. Cell Stress, 2022 Jan 17

  • Floros KV, Chawla AT, Johnson-Berro MO, Khatri R, Stamatouli AM, Boikos SA, Dozmorov MG, Cowart LA, Faber AC. MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma. Cell Stress. 2022 Jan 17. PMID, DOI

  • Rajesh Y, Reghupaty SC, Mendoza RG, Manna D, Banerjee I, Subler MA, Weldon K, Lai Z, Giashuddin S, Fisher PB, Sanyal AJ, Martin RK, Dozmorov MG, Windle JJ, Sarkar D. Dissecting the Balance Between Metabolic and Oncogenic Functions of Astrocyte-Elevated Gene-1/Metadherin. Hepatol Commun. 2021 Nov 5. PMID, DOI

  • Rashid NS, Hairr NS, Murray G, Olex AL, Leftwich TJ, Grible JM, Reed J, Dozmorov MG, Harrell JC. Identification of nuclear export inhibitor-based combination therapies in preclinical models of triple-negative breast cancer. Transl Oncol. 2021 Oct 7, PMID, DOI

  • Heisey DAR, Jacob S, Lochmann TL, Kurupi R, Ghotra MS, Calbert ML, Shende M, Kato Maves Y, Koblinski JE, Dozmorov MG, Boikos SA, Benes CH, Faber AC. Pharmaceutical interference of the EWS-FLI1-driven transcriptome by co-targeting H3K27ac and RNA polymerase activity in Ewing Sarcoma. Mol Cancer Ther. 2021 Jul 26. PMID, DOI

  • Kronfol MM, Abudahab S, Dozmorov MG, Jahr FM, Halquist MS, McRae M, Wijesinghe DS, Price ET, Slattum PW, McClay JL. Histone acetylation at the sulfotransferase 1a1 gene is associated with its hepatic expression in normal aging. Pharmacogenet Genomics. 2021 Jul 26. PMID, DOI

  • Fairchild CK Jr, Floros KV, Jacob S, Coon CM, Puchalapalli M, Hu B, Harada H, Dozmorov MG, Koblinski JE, Smith SC, Domson G, Leverson JD, Souers AJ, Takebe N, Ebi H, Faber AC, Boikos SA. Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA. Cancers (Basel). 2021 May 12, PMID, DOI

  • Dalton KM, Krytska K, Lochmann TL, Sano R, Casey C, D’Aulerio A, Khan QA, Stein Crowther G, Coon C, Cai J, Jacob S, Kurupi R, Hu B, Dozmorov M, Greninger P, Souers AJ, Benes CH, Mossé YP, Faber AC. Venetoclax-based rational combinations are effective in models of MYCN-amplified neuroblastoma. Mol Cancer Ther. 2021 Jun 4, PMID, DOI

  • Fuemmeler BF, Dozmorov MG, Do EK, Zhang JJ, Grenier C, Huang Z, Maguire RL, Kollins SH, Hoyo C, Murphy SK. DNA Methylation in Babies Born to Nonsmoking Mothers Exposed to Secondhand Smoke during Pregnancy: An Epigenome-Wide Association Study. Environ Health Perspect. 2021 May 19, PMID, DOI

  • Dalton KM, Lochmann TL, Floros KV, Calbert ML, Kurupi R, Stein GT, McClanaghan J, Murchie E, Egan RK, Greninger P, Dozmorov M, Ramamoorthy S, Puchalapalli M, Hu B, Shock L, Koblinski J, Glod J, Boikos SA, Benes CH, Faber AC. Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma. Proc Natl Acad Sci U S A. 2021 Mar 30, PMID, DOI

  • Iness AN, Rubinsak L, Meas SJ, Chaoul J, Sayeed S, Pillappa R, Temkin SM, Dozmorov MG, Litovchick L. Oncogenic B-Myb Is Associated With Deregulation of the DREAM-Mediated Cell Cycle Gene Expression Program in High Grade Serous Ovarian Carcinoma Clinical Tumor Samples. Front Oncol. 2021 PMID, DOI

  • Floros KV, Jacob S, Kurupi R, Fairchild CK, Hu B, Puchalapalli M, E Koblinski J, Dozmorov MG, Boikos SA, Scaltriti M, Faber AC. Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitor. Cell Death Dis. 2021 Feb 15. PMID, DOI

  • Bekhbat M, Mukhara D, Dozmorov MG, Stansfield JC, Benusa SD, Hyer MM, Rowson SA, Kelly SD, Qin Z, Dupree JL, Tharp GK, Tansey MG, Neigh GN. Adolescent stress sensitizes the adult neuroimmune transcriptome and leads to sex-specific microglial and behavioral phenotypes. Neuropsychopharmacology. 2021 Feb 8. PMID, DOI

  • James CD, Saini S, Sesay F, Ko K, Felthousen-Rusbasan J, Iness AN, Nulton T, Windle B, Dozmorov MG, Morgan IM, Litovchick L. Restoring the DREAM Complex Inhibits the Proliferation of High-Risk HPV Positive Human Cells. Cancers (Basel). 2021 Jan 27. PMID, DOI

  • Floros KV, Cai J, Jacob S, Kurupi R, Fairchild CK, Shende M, Coon CM, Powell KM, Belvin BR, Hu B, Puchalapalli M, Ramamoorthy S, Swift K, Lewis JP, Dozmorov MG, Glod J, Koblinski JE, Boikos SA, Faber AC. MYCN-amplified neuroblastoma is addicted to iron and vulnerable to inhibition of the system Xc-/glutathione axis. Cancer Res. 2021 Jan 22. PMID, DOI

  • Clark NM, Martinez LM, Murdock S, deLigio JT, Olex AL, Effi C, Dozmorov MG, Bos PD. Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ- Dependent Functional Reprogramming of Myeloid Cells. Cell Rep. 2020 Dec 8. PMID, DOI

  • Gurley JM, Gmyrek GB, McClellan ME, Hargis EA, Hauck SM, Dozmorov MG, Wren JD, Carr DJJ, Elliott MH. Neuroretinal-Derived Caveolin-1 Promotes Endotoxin-Induced Inflammation in the Murine Retina. Invest Ophthalmol Vis Sci. 2020 Oct 1. PMID, DOI

  • Drake J, McMichael GO, Vornholt ES, Cresswell K, Williamson V, Chatzinakos C, Mamdani M, Hariharan S, Kendler KS, Kalsi G, Riley BP, Dozmorov MG, Miles MF, Bacanu SA, Vladimirov VI. Assessing the Role of Long-Noncoding RNA in Nucleus Accumbens in Subjects with Alcohol Dependence. Alcohol Clin Exp Res. 2020 Oct 17. PMID, DOI

  • Patel VI, Booth JL, Dozmorov M, Brown BR, Metcalf JP. Anthrax Edema and Lethal Toxins Differentially Target Human Lung and Blood Phagocytes. Toxins (Basel). 2020 Jul 20. PMID, DOI

  • Joachims ML, Leehan KM, Dozmorov MG, Georgescu C, Pan Z, Lawrence C, Marlin MC, Macwana S, Rasmussen A, Radfar L, Lewis DM, Stone DU, Grundahl K, Scofield RH, Lessard CJ, Wren JD, Thompson LF, Guthridge JM, Sivils KL, Moore JS, Farris AD. Sjögren’s Syndrome Minor Salivary Gland CD4+ Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile. J Clin Med. 2020 Jul 8. PMID, DOI

  • Cai Q, Dozmorov M, Oh Y. IGFBP-3/IGFBP-3 Receptor System as an Anti-Tumor and Anti-Metastatic Signaling in Cancer. Cells. 2020 May 20. PMID, DOI

  • Kronfol MM, Jahr FM, Dozmorov MG, Phansalkar PS, Xie LY, Aberg KA, McRae M, Price ET, Slattum PW, Gerk PM, McClay JL. DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver. Geroscience. 2020 Mar 27. PMID, DOI

  • Saunders JM, Moreno JL, Ibi D, Sikaroodi M, Kang DJ, Munoz-Moreno R, Dalmet SS, Garcia-Sastre A, Gillevet PM, Dozmorov MG, Bajaj JS, Gonzalez-Maeso J. Gut microbiota manipulation during the prepubertal period shapes behavioral abnormalities in a mouse neurodevelopmental disorder model. Sci Rep. 2020 Mar 13. PMID, DOI

  • Wang D, Naydenov NG, Dozmorov MG, Koblinski JE, Ivanov AI. Anillin regulates breast cancer cell migration, growth, and metastasis by non-canonical mechanisms involving control of cell stemness and differentiation. Breast Cancer Res. 2020 Jan 7. PMID, DOI

  • Mirshahi F, Aqbi HF, Cresswell K, Saneshaw M, Coleman C, Jacobs T, Idowu MO, Dozmorov M, Sanyal AJ, Manjili MH. Longitudinal studies can identify distinct inflammatory cytokines associated with the inhibition or progression of liver cancer. Liver Int. 2019 Dec 10. PMID, DOI

  • Sayyad MR, Puchalapalli M, Vergara NG, Wangensteen SM, Moore M, Mu L, Edwards C, Anderson A, Kall S, Sullivan M, Dozmorov M, Singh J, Idowu MO, Koblinski JE. Syndecan-1 facilitates breast cancer metastasis to the brain. Breast Cancer Res Treat. 2019 Jul 20. PMID, DOI

  • Buchta Rosean C, Bostic RR, Ferey JCM, Feng TY, Azar FN, Tung KS, Dozmorov MG, Smirnova E, Bos PD, Rutkowski MR. Pre-existing commensal dysbiosis is a host-intrinsic regulator of tissue inflammation and tumor cell dissemination in hormone receptor-positive breast cancer. Cancer Res. 2019 May 7. PMID, DOI

  • Yu X, Azzo A, Bilinovich SM, Li X, Dozmorov M, Kurita R, Nakamura Y, Williams DC Jr, Ginder GD. Disruption of the MBD2-NuRD complex but not MBD3-NuRD induces high level HbF expression in human erythroid cells. Haematologica. 2019 Apr 19. PMID, DOI

  • Alzubi MA, Turner TH, Olex AL, Sohal SS, Tobin NP, Recio SG, Bergh J, Hatschek T, Parker JS, Sartorius CA, Perou CM, Dozmorov MG, Harrell JC. Separation of breast cancer and organ microenvironment transcriptomes in metastases. Breast Cancer Res. 2019 Mar 6. PMID, DOI

  • R Menon V, Ananthapadmanabhan V, Swanson S, Saini S, Sesay F, Yakovlev V, Florens L, DeCaprio JA, P Washburn M, Dozmorov M, Litovchick L. DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169. Cell Cycle. 2019 Feb 17. PMID, DOI

  • Reimers MA, Craver C, Dozmorov M, Bacanu SA, Kendler KS. The Coherence Problem: Finding Meaning in GWAS Complexity. Behav Genet. 2018 Nov 16. PMID, DOI

  • Towner RA, Smith N, Saunders D, Brown CA, Cai X, Ziegler J, Mallory S, Dozmorov MG, Coutinho De Souza P, Wiley G, Kim K, Kang S, Kong DS, Kim YT, Fung KM, Wren JD, Battiste J. OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth. Transl Oncol. 2018 Nov 20. PMID, DOI

  • Iness AN, Felthousen J, Ananthapadmanabhan V, Sesay F, Saini S, Guiley KZ, Rubin SM, Dozmorov M, Litovchick L. The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb. Oncogene. 2018 Sep 11. PMID, DOI

  • Mazzini GS, Khoraki J, Dozmorov M, Browning MG, Wijesinghe D, Wolfe L, Gurski RR, Campos GM. Concomitant PPARα and FXR Activation as a Putative Mechanism of NASH Improvement after Gastric Bypass Surgery: a GEO Datasets Analysis. J Gastrointest Surg. 2018 Sep 11. PMID, DOI

  • Robertson CL, Mendoza RG, Jariwala N, Dozmorov M, Mukhopadhyay ND, Subler MA, Windle JJ, Lai Z, Fisher PB, Ghosh S, Sarkar D. Astrocyte Elevated Gene-1 Regulates Macrophage Activation in Hepatocellular Carcinogenesis. Cancer Res. 2018 Sep 4. PMID, DOI

  • Wu W, Wang X, Zhang W, Tian L, Booth JL, Duggan ES, More S, Liu L, Dozmorov M, Metcalf JP. RIG-I Signaling via MAVS Is Dispensable for Survival in Lethal Influenza Infection In Vivo. Mediators Inflamm. 2018 Nov 8. PMID, DOI

  • de la Fuente Revenga M, Ibi D, Saunders JM, Cuddy T, Ijaz MK, Toneatti R, Kurita M, Holloway T, Shen L, Seto J, Dozmorov MG, González-Maeso J. HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice. Neuroscience. 2018 Jul 17. PMID, DOI

  • Martínez-Bueno M, Oparina N, Dozmorov MG, Marion MC, Comeau ME, Gilkeson G, Kamen D, Weisman M, Salmon J, McCune JW, Harley JB, Kimberly R, James JA, Merrill J, Montgomery C, Langefeld CD, Alarcón-Riquelme ME. Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks. Int J Mol Sci. 2018 Aug 8. PMID, DOI

  • Booth JL, Duggan ES, Patel VI, Wu W, Burian DM, Hutchings DC, White VL, Coggeshall KM, Dozmorov MG, Metcalf JP. Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines. Microb Pathog. 2018 Apr 25. PMID, DOI

  • Turner TH, Alzubi MA, Sohal SS, Olex AL, Dozmorov MG, Harrell JC. Characterizing the efficacy of cancer therapeutics in patient-derived xenograft models of metastatic breast cancer. Breast Cancer Res Treat. 2018 Mar 12. PMID, DOI

  • Lochmann TL, Powell KM, Ham J, Floros KV, Heisey DAR, Kurupi RIJ, Calbert ML, Ghotra MS, Greninger P, Dozmorov M, Gowda M, Souers AJ, Reynolds CP, Benes CH, Faber AC. Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma. Sci Transl Med. 2018 May 16. PMID, DOI

  • Floros KV, Lochmann TL, Hu B, Monterrubio C, Hughes MT, Wells JD, Bernadó Morales C, Ghotra MS, Costa C, Souers AJ, Boikos SA, Leverson JD, Tan M, Serra V, Koblinski JE, Arribas J, Prat A, Paré L, Miller TW, Dozmorov MG, Harada H, Windle BE, Scaltriti M, Faber AC. Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy. Proc Natl Acad Sci U S A. 2018 Feb 23. PMID, DOI

  • Song KA, Niederst MJ, Lochmann TL, Hata AN, Kitai H, Ham J, Floros KV, Hicks MA, Hu H, Mulvey HE, Drier Y, Heisey DAR, Hughes MT, Patel NU, Lockerman EL, Garcia A, Gillepsie S, Archibald HL, Gomez-Caraballo M, Nulton TJ, Windle BE, Piotrowska Z, Sahingur SE, Taylor SM, Dozmorov M, Sequist LV, Bernstein B, Ebi H, Engelman JA, Faber AC. Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM. Clin Cancer Res. 2018 Jan 1. PMID, DOI

  • Wren JD, Dozmorov MG, Toby I, Nanduri B, Homayouni R, Manda P, Thakkar S. Proceedings of the 2017 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. BMC Bioinformatics. 2017 Dec 28. PMID, DOI

  • Masser DR, Hadad N, Porter HL, Mangold CA, Unnikrishnan A, Ford MM, Giles CB, Georgescu C, Dozmorov MG, Wren JD, Richardson A, Stanford DR, Freeman WM. Sexually divergent DNA methylation patterns with hippocampal aging. Aging Cell. 2017 Sep 25. PMID, DOI

  • Sai Vineela Bontha, Ricardo Gehrau, Sihee L. Suh, Catherine I. Dumur, Mikhail Dozmorov, Kellie J. Archer, Daniel G. Maluf, Lorenzo Gallon, Valeria R. Mas. Effects of DNA Methylation on Progression to Interstitial Fibrosis and Tubular Atrophy in Renal Allograft Biopsies: A Multi-omics Approach. American Journal of Transplantation, 2017 May 28. PMID, DOI

  • Liu Y, Walavalkar NM, Dozmorov MG, Rich SS, Civelek M, Guertin MJ. Identification of breast cancer associated variants that modulate transcription factor binding. PLoS Genet. 2017 Sep 28. PMID, DOI

  • Srivastava J, Robertson CL, Ebeid K, Dozmorov M, Rajasekaran D, Mendoza R, Siddiq A, Akiel MA, Jariwala N, Shen XN, Windle JJ, Subler MA, Mukhopadhyay ND, Giashuddin S, Ghosh S, Lai Z, Chen Y, Fisher PB, Salem AK, Sanyal AJ, Sarkar D. A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH). Hepatology. 2017 Jun 30. PMID, DOI

  • Hylemon PB, Takabe K, Dozmorov M, Nagahashi M, Zhou H. Bile acids as global regulators of hepatic nutrient metabolism. Liver Res. 2017 Jun 1. PMID, DOI

  • Dumancas, GG, Adrianto I, Bello G, Dozmorov M. Current Developments in Machine Learning Techniques in Biological Data Mining. Bioinformatics and Biology Insights. 2017. PMID, DOI

  • Nulton TJ, Olex AL, Dozmorov M, Morgan IM, Windle B. Analysis of the cancer genome atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell carcinoma. Oncotarget. 2017. PMID, DOI

  • Ramanathan R, Olex AL, Dozmorov M, Bear HD, Fernandez LJ, Takabe K. Angiopoietin pathway gene expression associated with poor breast cancer survival. Breast Cancer Res Treat. 2017. PMID, DOI

  • Patel VI, Booth JL, Duggan ES, Cate S, White VL, Hutchings D, Kovats S, Burian DM, Dozmorov M, Metcalf JP. Transcriptional Classification and Functional Characterization of Human Airway Macrophage and Dendritic Cell Subsets. J Immunol. 2017. PMID, DOI

  • Kronfol MM, Dozmorov MG, Huang R, Slattum PW, McClay JL. The role of epigenomics in personalized medicine. Expert Rev Precis Med Drug Dev. 2017. PMID, DOI

  • Ward JM, Ratliff ML, Dozmorov MG, Wiley G, Guthridge JM, Gaffney PM, James JA, Webb CF. Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels. Data Brief. 2016 Aug 31. PMID, DOI

  • Ward JM, Ratliff ML, Templeton TD, Dozmorov MG, Wiley G, Guthridge JM, Gaffney PM, James JA, Webb CF Human effector B lymphocytes express ARID3a and secrete interferon alpha J Autoimmun. 2016 Aug 10. PMID, DOI

  • Wren JD, Toby I, Hong H, Nanduri B, Kaundal R, Dozmorov MG, Thakkar S. Proceedings of the 2016 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. BMC Bioinformatics. 2016. PMID, DOI

  • Kushwaha G, Dozmorov MG, Wren JD, Qui J, Shi H, Xu D Hypomethylation Coordinates Antagonistically with Hypermethylation in Cancer Development: A Case Study of Leukemia. Hum Genomics. 2016 Jul 25. PMID, DOI

  • van den Oord EJ, Clark SL, Xie LY, Shabalin AA, Dozmorov MG, Kumar G, Swedish Schizophrenia Consortium, Vladimirov VI, Magnusson PKE, Aberg KA. A whole methylome CpG-SNP association study of psychosis in blood and brain tissue. Schizophrenia Bulletin. 2015 Dec 9. PMID, DOI

  • Rajasekaran D, Jariwala N, Gredler R, Robertson CL, Akiel AM, Dozmorov M, Fisher PB, Sarkar D. Staphylococcal nuclease and tudor domain containing 1 (SND1) promotes hepatocarcinogenesis by inhibiting monoglyceride lipase (MGLL). J Biol Chem. 2016 Mar 20. PMID, DOI

  • Wright ML, Dozmorov MG, Wolen AR, Jackson-Cook C, Starkweather AR, Lyon DE, York TP Establishing an analytic pipeline for genome-wide DNA methylation. Clinical Epigenetics 2016 Apr 26. PMID, DOI

  • Sun C, Molineros JE, Looger LL, Zhou XJ, Kim K, Okada Y, Ma J, Qi YY, Kim-Howard X, Motghare P, Bhattarai K, Adler A, Bang SY, Lee HS, Kim TH, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, Shim SC, Kochi Y, Suzuki A, Kubo M, Sumida T, Yamamoto K, Lee SS, Kim YJ, Han BG, Dozmorov M, Kaufman KM, Wren JD, Harley JB, Shen N, Chua KH, Zhang H, Bae SC, Nath SK. High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry. Nat Genet. 2016 Jan 25. PMID, DOI

  • Ham J, Costa C, Sano R, Lochmann TL, Sennott EM, Patel NU, Dastur A, Gomez-Caraballo M, Krytska K, Hata AN, Floros KV, Hughes MT, Jakubik CT, Heisey DA, Ferrell JT, Bristol ML, March RJ, Yates C, Hicks MA, Nakajima W, Gowda M, Windle BE, Dozmorov MG, Garnett MJ, McDermott U, Harada H, Taylor SM, Morgan IM, Benes CH, Engelman JA, Mossé YP, Faber AC. Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination. Cancer Cell. 2016 Feb 8. PMID, DOI

  • Sawalha AH, Dozmorov MG Epigenomic functional characterization of genetic susceptibility variants in systemic vasculitis. J Autoimmun. 2015 Oct 19. PMID, DOI

  • McClay JL, Shabalin AA, Dozmorov MG, Adkins DE, Kumar G, Nerella S, Clark SL, Bergen SE, Hultman CM, Magnusson PKE, Sullivan PF, Aberg KA, van den Oord EJ. High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction. Genome Biology. 2015 Dec 23. PMID, DOI

  • Wren JD, Thakkar S, Homayouni R, Johann DJ, Dozmorov MG Proceedings of the 2015 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. BMC Bioinformatics. 2015 Sep 25. PMID, DOI

  • Iwayama T., Steele C., Yao L., Dozmorov MG, Karamichos D., Wren JD., Olson LE. PDGFRalpha signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity. Genes Dev. 2015 Jun 1. PMID, DOI

  • Tulunay A, Dozmorov MG, Ture-Ozdemir F, Yilmaz V, Eksioglu-Demiralp E, Alibaz-Oner F, Ozen G, Wren JD, Saruhan-Direskeneli G, Sawalha AH, Direskeneli H. Activation of the JAK/STAT pathway in Behcet’s disease. Genes Immun. 2014 Nov 20. PMID, DOI

  • Wren JD, Dozmorov MG, Burian D, Perkins A, Zhang C, Hoyt P, Kaundal R. Proceedings of the 2014 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. BMC Bioinformatics. 2014. PMID, DOI

  • Lessard CJ, Li H, Adrianto I, Ice JA, Rasmussen A, Grundahl KM, Kelly JA, Dozmorov MG, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Jazebi H, Graham DS, Grandits ME, Nazmul-Hossain AN, Patel K, Adler AJ, Maier-Moore JS, Farris AD, Brennan MT, Lessard JA, Chodosh J, Gopalakrishnan R, Hefner KS, Houston GD, Huang AJ, Hughes PJ, Lewis DM, Radfar L, Rohrer MD, Stone DU, Wren JD, Vyse TJ, Gaffney PM, James JA, Omdal R, Wahren-Herlenius M, Illei GG, Witte T, Jonsson R, Rischmueller M, Rönnblom L, Nordmark G, Ng WF; for UK Primary Sjögren’s Syndrome Registry, Mariette X, Anaya JM, Rhodus NL, Segal BM, Scofield RH, Montgomery CG, Harley JB, Sivils KL. Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome. Nat Genet. 2013 Oct 6. PMID, DOI

  • Wren JD, Dozmorov MG, Burian D, Kaundal R, Perkins A, Perkins E, Kupfer DM, Springer GK. Proceedings of the 2013 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. BMC Bioinformatics. 2013 Oct 9. PMID, DOI

  • Giles CB, Girija-Devi R, Dozmorov MG, Wren JD. mirCoX: A database of miRNA-mRNA expression correlations derived from RNA-seq meta-analysis. BMC Bioinformatics. 2013, Oct 9. PMID, DOI

  • Wan X, Sato H, Miyaji H, McDaniel JM, Wang Y, Kaneko E, Gibson B, Mehta JP, Dozmorov M, Miller LP, Goodman J, Sun Z, Xia L. Fucosyltransferase VII improves the function of selectin ligands on cord blood hematopoietic stem cells. Glycobiology. 2013 Jul 29. PMID, DOI

  • Coit P, Jeffries M, Altorok N, Dozmorov MG, Koelsch KA, Wren JD, Merrill JT, McCune WJ, Sawalha AH. Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients. J Autoimmun. 2013 Apr 24. PMID, DOI

  • Hurst RE, Hauser PJ, Kyker KD, Heinlen JE, Hodde JP, Hiles MC, Kosanke SD, Dozmorov M, Ihnat MA. Suppression and Activation of the Malignant Phenotype by Extracellular Matrix in Xenograft Models of Bladder Cancer: A Model for Tumor Cell Dormancy. PLoS One. 2013 May 24. PMID, DOI

  • Koelsch KA, Webb R, Jeffries M, Dozmorov MG, Frank MB, Guthridge JM, James JA, Wren JD, Sawalha AH. Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse. J Autoimmun. 2013 Mar 14. PMID, DOI

  • Wren JD, Dozmorov MG, Burian D, Kaundal R, Bridges S, Kupfer DM. Proceedings of the 2012 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) conference. BMC Bioinformatics. 2012, Sept 11. PMID, DOI

  • Sahoo K, Dozmorov MG, Anant S, Awasthi V. The curcuminoid CLEFMA selectively induces cell death in H441 lung adenocarcinoma cells via oxidative stress. Invest New Drugs. 2012 Apr 12. PMID, DOI

  • Wren JD, Kupfer DM, Perkins EJ, Bridges S, Winters-Hilt S, Dozmorov MG, Braga-Neto U. Proceedings of the 2011 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) conference. BMC Bioinformatics. 2011 Oct 18. PMID, DOI

  • Jeffries MA, Dozmorov M, Tang Y, Merrill JT, Wren JD, Sawalha AH. Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus. Epigenetics. 2011 May 6. PMID, DOI

  • Abbas AK, Dozmorov M, Li R, Huang FS, Hellberg F, Danielson J, Tian Y, Ekström J, Sandberg M, Wigström H. Persistent LTP without triggered protein synthesis. Neurosci Res. 2009 Jan 11. PMID, DOI

  • Hauser PJ, Dozmorov MG, Bane BL, Slobodov G, Culkin DJ, Hurst RE. Abnormal expression of differentiation related proteins and proteoglycan core proteins in the urothelium of patients with interstitial cystitis. J Urol. 2008 Feb. PMID, DOI

  • Hurst RE, Kyker KD, Dozmorov MG, Takemori N, Singh A, Matsumoto H, Saban R, Betgovargez E, Simonian MH. Proteome-level display by 2-dimensional chromatography of extracellular matrix-dependent modulation of the phenotype of bladder cancer cells. Proteome Sci. 2006 Jun 2. PMID, DOI

  • Li R, Dozmorov MG, Hellberg F, Tian Y, Jilderos B, Wigström H. Characterization of NMDA induced depression in rat hippocampus: involvement of AMPA and NMDA receptors. Neurosci Lett. 2004 Mar 4. PMID, DOI

  • Xiao MY, Niu YP, Dozmorov MG, Wigström H. Comparing fluctuations of synaptic responses mediated via AMPA and NMDA receptor channels–implications for synaptic plasticity. Biosystems. 2001 Sep. PMID, DOI

Book chapters

  • Green CD, Dozmorov MG, Spiegel S. Analysis of Liver Responses to Non-alcoholic Steatohepatitis by mRNA-Sequencing. Methods Mol Biol. 01 January 2022. PMID, DOI

  • Dozmorov MG, Hurst RE. Systems Biology for Signaling Networks, Chapter 4, From Microarray to Biology, Springer Science+Business Media, LLC 2010 DOI

Preprints

bioRxiv search results